双支架技术:自体碎软骨与骨髓抽吸物支架联合合成胶原膜修复软骨
简介
该研究介绍了一种单阶段膝关节软骨修复新技术:将自体碎软骨与骨髓抽吸物混合,再结合合成胶原膜构建双支架。该方法利用骨髓间充质干细胞和自体软骨支架的软骨分化与旁分泌能力,旨在改善全层软骨缺损的修复效果,提供一种生物学增强的临床选择。
英文摘要
Treating cartilage injuries has long been a complex challenge; however, recent progress has greatly increased the variety of effective therapeutic approaches. The minced autologous matrix-induced chondrogenesis plus procedure for full-thickness knee cartilage lesions uses a collagen matrix combined with shaver-minced cartilage graft and bone marrow aspirate. It merges a source of bone marrow-derived stem cells and a biological autologous cartilage scaffold, leveraging their chondrogenic differentiation capacity and paracrine activity. This technique aims to enhance outcomes and provides an associated single-stage knee cartilage repair option with biological augmentation.