膝关节镜手术中止血带压力的优化：一项关于当前实践的国际调查及双盲随机试验
简介
一项国际调查及双盲随机对照试验发现，膝关节镜手术中采用个体化最小有效闭塞压力（MEIOP，平均约230 mmHg）相比常规固定压力（350 mmHg），可显著降低术后6小时及15天内的疼痛评分（VAS），且两组手术视野均达到100%优秀评级。该研究提示，基于多普勒测定的肢体闭塞压力加安全余量设定止血带压力，能在保证视野清晰的同时减少术后疼痛。
英文摘要
BACKGROUND & PURPOSE: Pneumatic tourniquets improve surgical visualization during knee arthroscopy, but fixed high pressures may increase postoperative pain. This study investigated whether a minimal effective individualized occlusion pressure (MEIOP), calculated as limb occlusion pressure plus a safety margin, maintains surgical field quality while reducing pain compared to a standardized occlusion pressure (SOP). METHODS: A preliminary survey of 79 orthopaedic surgeons identified 350 mmHg as the routine SOP. In a subsequent double-blind randomized clinical trial, patients undergoing elective knee arthroscopy were assigned to SOP (350 mmHg) or MEIOP, defined as Doppler-derived limb occlusion pressure plus a safety margin (mean ≈ 230 mmHg). Outcomes included surgical field quality, postoperative using a visual analog scale (VAS) up to 15 days, overall 15-day pain perception, and analgesic consumption. RESULTS: Both groups achieved 100% excellent surgical field ratings. Pain trajectories differed significantly between groups over time (group × time interaction, p = 0.022). The MEIOP group experienced significantly lower pain at discharge (~ 6 h; p = 0.013, d = 1.14) and lower overall 15-day pain perception (p = 0.043, d = 0.89). Analgesic consumption showed a consistent descriptive trend favoring MEIOP throughout follow-up. CONCLUSION: This proof-of-concept study suggests that individualizing tourniquet pressure using predefined MEIOP protocol preserves satisfactory surgical visualization and is associate with lower postoperative pain compared with a standard high-pressure protocol. This trial was prospectively registered at the Brazilian Clinical Trials Registry (ReBEC; RBR-4xd6cxm).