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富血小板血浆促进创伤性半月板修复术后早期功能恢复及重返运动:一项回顾性队列研究

Journal of orthopaedic surgery and research · 2026-Jun-22
阅读数 0
Lei Tian, Zou Yujia, Zhao Yan, Guo Qin, Zhang Shangqing, Jing Zhaopu et al.

简介

一项回顾性队列研究纳入96例创伤性半月板撕裂患者(每组48例),比较关节镜修复联合富血小板血浆(PRP)注射与单纯修复的疗效。术后6个月时,PRP组在IKDC评分、Tegner活动量表和VAS评分上的改善均显著优于单纯手术组(p均<0.05),且差异超过最小临床重要差异(MCID);MRI愈合率也更高(p=0.014)。术后12个月时,PRP组IKDC和VA…

英文摘要

PURPOSE: To investigate the clinical efficacy of arthroscopic repair combined with platelet-rich plasma (PRP) injection for traumatic meniscal tears. METHODS: A retrospective cohort study included patients who underwent arthroscopic repair for traumatic meniscal tears between January 2023 and August 2024. Clinical outcomes were evaluated preoperatively and at 6 and 12 months postoperatively using the International Knee Documentation Committee (IKDC) score, Tegner activity scale (Tegner scale), and visual analogue scale (VAS). MRI healing rate, return to sport (RTS) outcomes, and postoperative satisfaction were evaluated. Subgroup analyses were conducted for patients with preoperative bone marrow edema (BME). RESULTS: A total of 96 patients were included (48 per group), with comparable baseline characteristics. At 6 months, the PRP group demonstrated significantly greater improvements in IKDC score, Tegner scale and VAS than the surgery-alone group (p < 0.001, p = 0.036, and p < 0.001, respectively), with differences exceeding the minimal clinically important differences (MCIDs). MRI healing rate was higher in the PRP group (p = 0.014). By 12 months, improvements in IKDC score and VAS remained superior in the PRP group though differences no longer exceeded MCIDs. Tegner scale and MRI healing rates were comparable (p = 0.265 and 0.088, respectively). The PRP group achieved superior RTS outcomes. Satisfaction (≥ satisfied) was high in both groups (95.8% vs. 89.6%). In the PRP group, postoperative IKDC scores did not differ significantly between patients with and without BME, whereas in the surgery-alone group, scores were significantly lower in those with BME. CONCLUSIONS: PRP augmentation for traumatic meniscal repair may provide clinically improvements at 6 months postoperatively, including better IKDC score, Tegner scale, and VAS, a higher meniscal healing rate, and facilitate earlier RTS. However, these benefits diminished by 12 months, with functional differences falling below the MCID and no sustained difference in healing rate. Patients with preoperative BME may derive greater functional benefit from adjunctive PRP treatment.

关键词

Arthroscopic repair Functional improvement Platelet-rich plasma Return to sport Traumatic meniscal tear

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