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保留残端的前交叉韧带重建术使用自体腘绳肌腱移植物获得最低再断裂率:系统评价与Meta分析

Journal of experimental orthopaedics · 2026-Apr
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Basal Ozgur, Jefferies James G, Serdar Jure, Papakostas Emmanuel, Karakas Furkan, Huri Gazi et al.

简介

这项系统评价与Meta分析比较了保留残端ACL重建(RP-ACLR)与传统牺牲残端技术(NP-ACLR)的移植物存活率、并发症及再手术率,并按移植物类型进行亚组分析。共纳入34项研究(4368例患者),其中RP组2759例,NP组1609例。关键发现:RP组移植物再断裂率显著低于NP组(风险比=0.58,95%置信区间0.41-0.83),再手术率无显著差异…

英文摘要

PURPOSE: Remnant-preserving anterior cruciate ligament reconstruction (RP-ACLR) has garnered interest due to its potential biological benefits. This study aimed to compare graft survival, complication and reoperation rates between RP-ACLR and standard remnant-sacrificing techniques (non-remnant-preserving ACLR [NP-ACLR]), with subgroup analysis by graft type. METHODS: A systematic literature search was conducted in PubMed, Embase and Cochrane Library up to June 2025. Study selection, data extraction and risk-of-bias assessment (using Risk of Bias In Non-randomized Studies of Interventions [ROBINS-I]) were performed independently by two reviewers, with discrepancies resolved by a third. Inclusion criteria comprised clinical studies (Levels I-III) reporting complications or reoperations after RP-ACLR. Pooled rates were calculated using random-effects meta-analysis where appropriate. RESULTS: Across 34 studies (n = 4368 patients), the RP group comprised 2759 patients and the NP group 1609 patients. Graft re-rupture was significantly lower in the RP group (risk ratio [RR] = 0.58, 95% confidence interval [CI] 0.41-0.83), while reoperation rates did not differ significantly (RR = 1.12, 95% CI 0.56-2.22). Patient-reported outcomes favoured RP-ACLR, with a significant improvement in Lysholm scores. Subgroup analysis revealed the lowest re-rupture rate with hamstring autograft and remnant preservation (2.8%). Second-look arthroscopy demonstrated superior graft synovial coverage in RP patients (~85% vs. ~59%) and a lower incidence of cyclops lesions (pooled rate 9.4%). CONCLUSION: RP-ACLR is a safe and clinically beneficial technique that demonstrates significantly lower rates of graft failure and comparable complication and reoperation rates versus standard ACLR. These findings support remnant preservation in appropriately selected patients to enhance graft survival. LEVEL OF EVIDENCE: Level IV.

关键词

anterior cruciate ligament graft failure hamstring autograft meta‐analysis remnant preservation

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